NATAP: 158 links to journal reports & studies on HIV/AIDS & aging (027)

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richardkearns.awo.randbvertical-0821081833chers—

this is the national aids treatment advocacy project’s (NATAP’s) selected linklist to 158 medical study reports & journal articles on HIV/AIDS & aging. i am hoping that at some future point, when HAVVACC has collected & transcribed enough anecdotal material, i can have a search engine hooked up to the site to produce matches from multiple genres.

we’ll see how it turns out.

if you want to help out, drop me a line at rk@aids.write.org.

if you want to check it out, take a deep breath, be brave, and click on a link. figure out where it takes you after you get there.

as an example, i will cut & paste the most recent study in the next post.

namasté

—rk

natap-HIVAging-1-header

  • HIV and Aging: The Long-term Consequences of Successful Antiretroviral Therapy – (09/11/09)
  • HIV, HAART & Brain Damage & Repair – (09/11/09)
  • HIV-1 RNA concentration and cognitive performance in a cohort of HIV-positive people – (08/29/09)
  • Neurological Impairment Persists Despite HAART: “adjunctive therapies needed” – (08/29/09)
  • Insulin Resistance Is Associated With Cognition Among HIV-1-Infected Patients: The Hawaii Aging With HIV Cohort – (08/29/09)
  • HCV Coinfection & Neurologic Impairment – (08/29/09)
  • 5th IAS: Prevalence of HIV-1-Associated Neurocognitive Disorders in Argentina – (08/27/09)
  • Oxidized lipids enhance RANKL production by T lymphocytes: Implications for lipid-induced bone loss – pdf attached – (08/27/09)
  • The clot thickens-oxidized lipids and thrombosis – (08/26/09)
  • Oxidized lipids: a key to heart disease? – (08/26/09)
  • Aging/HIV Clinical Care & Research – New IDSA Guidelines – (08/26/09)
  • Thyroid Dysfunction, Hypogonadism, Testosterone, Bone, Prostate Cancer, HIV & HAART – (08/26/09)
  • Aging & HIV Recognized as a Serious Concern But No Real Discussion, Still Ignored. 2007 NIH Workshop recommendations – (08/26/09)
  • NIH Workshop on HIV in Older Adults Oct 20 2007 – (08/18/09)
  • A serum 25-hydroxyvitamin D level below 50 nmol/l has been associated with increased body sway and a level below 30 nmol/l with decreased muscle strength. – (08/18/09)
  • Vitamin D deficiency, muscle function, and falls in elderly people1,2 Review Article – (08/18/09)
  • 5th IAS: One Third With Undetectable HIV RNA Have Asymptomatic Neurocognitive Impairment – written by Mark Mascolini – (07/20/09)
  • 5th IAS: Thinking Through the CNS: The Importance of Considering the Blood-Brain Barrier. Slide talk by Scott Letende, GSK satellite meeting at IAS 2009 – (07/19/09)
  • 5th IAS: European Researchers Issuing Guidelines on Bone Disease – (07/19/09)
  • HIV-1 Infection Is Associated With an Earlier Occurrence of Frailty….in MACS – (07/18/09)
  • Growth Hormone and Sex Steroid Effects on Serum Glucose, Insulin, and Lipid Concentrations in Healthy Older Women and Men – (07/16/09)
  • MRI Findings May Track Risk of Cognitive Impairment in Healthy Seniors – (07/16/09)
  • Lower Testosterone Levels Predict Incident Stroke and Transient Ischemic Attack in Older Men – (07/16/09)
  • Low Serum Testosterone and Estradiol Predict Mortality in Elderly Men – (07/16/09)
  • Nitrates May Be Environmental Trigger For Alzheimer’s, Diabetes And Parkinson’s Disease – (07/08/09)
  • Global Consequences of the Future of Aging with HIV – (07/08/09)
  • A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection – full text pdf attached – (07/07/09)
  • IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection – pdf full text attached – (07/07/09)
  • IL-21 Is Required to Control Chronic Viral Infection – pdf full text attached – (07/07/09)
  • Immunology Controlling Chronic Viral Infections, EDITORS’ CHOICE – (07/07/09)
  • A Chronic Need for IL-21 EDITORIAL – (07/07/09)
  • Metabolic bone disease in HIV infection: HIV, ART Implicated EDITORIAL – (07/02/09)
  • First line AZT/3TC/lopinavir/ritonavir leads to greater bone loss compared to nevirapine/lopinavir/ritonavir – (07/02/09)
  • The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials – (07/02/09)
  • Inflammation Marker hsCRP & CVD- Cause or Effect: Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease – (07/02/09)
  • Novel and Conventional Biomarkers for Prediction of Incident Cardiovascular Events in the Community: “Minimal Benefit In Predicting CVD Compared To Traditional Risk Factors” – (07/02/09)
  • Biomarkers and Cardiovascular Disease: Determining Causality and Quantifying Contribution to Risk Assessment – Editorial – (07/02/09)
  • CRP, other biomarkers, not clinically useful to predict CVD risk – (07/02/09)
  • New meta-analysis: Statins of benefit in primary prevention: improved survival & CVD risk in patients with only risk factors – (07/02/09)
  • Monitoring bone mineral density during antiresorptive treatment for osteoporosis – Editorial – (06/27/09)
  • Value of routine monitoring of bone mineral density after starting bisphosphonate treatment: secondary analysis of trial data – (06/27/09)
  • The Value of Bone Density Testing – (06/27/09)
  • Early antiretroviral treatment prevents the development of central nervous system abnormalities in simian immunodeficiency virus-infected rhesus monkeys – (06/19/09)
  • Study in Neurology journal (Aug 2008) Reports Alzheimers Appears to Precede Frailty and Study in Jnl of Geronotology (2007) in the MACS Cohort Reports Risk of Frailty Higher in HIV+ vs HIV-; is early onset of Alzheimers or some other brain or cognitive dysfunction related to early onset and higher rates of frailty among HIV+? – (06/08/09)
  • Antiaging Therapy with TAT2: Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes – (06/02/09)
  • Modulation of T Lymphocyte Replicative Senescence via TNF-{alpha} Inhibition: Role of Caspase-31 – (06/01/09)
  • Does HIV Increase Prostate Cancer Risk? – (05/21/09)
  • Effects of Oxidation and Inflammation, Cancer, Prostate Cancer – (05/21/09)
  • Predicting risk of dementia in older adults. The late-life dementia risk index – Aging !!!! – (05/15/09)
  • RNA Testing for HIV Instead of Antibody Testing Could Detect Early Stage of HIV Infection And Would Likely Improve Prevention AND Allow for Early HAART’ Could it Prevent Accelerated Aging? – (05/13/09)
  • Dementia with features of Alzheimer’s disease and HIV-associated dementia in an elderly man with AIDS (case study) – (05/13/09)
  • Cancers in HIV Review in AIDS May 15 2009 – (05/13/09)
  • HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial – (05/13/09)
  • Glucocorticoid-induced osteoporosis: hope on the HORIZON-COMMENT – (04/20/09)
  • Reversing HIV T-Cell Aging – (04/20/09)
  • HIV-1 Infection Is Associated With an Earlier Occurrence of a Phenotype Related to Frailty: HIV+ men in MACS 10-Times More Likely to Exhibit Frailty than HIV-negative Men. – (04/20/09)
  • MACS Frailty/HIV/CD4 Study Misses The Point – (04/20/09)
  • Midlife Patients With HIV or AIDS Require Care for Chronic Conditions: “HIV simulates aging” – (03/27/09)
  • ISHLVD: Developing HBV/HCV Associated Liver Cancer At A Young Age < 40 Yrs Old – (03/25/09)
  • How Inflammatory Disease Causes Fatigue: chronic inflammation infiltrates the brain but can be blocked – (03/10/09)
  • WHO | The unexplored story of HIV and ageing – (03/05/09)
  • CROI: Effects of Aging on HIV-1 Pathogenesis: HIV causes inflammation & T-cell activation, reported here to be more in postmenopausal women – (03/04/09)
  • CROI: Immune Senescence, Activation and Abnormal T cell Homeostasis Despite Effective HAART, A Hallmark of Early Aging in HIV Disease – (03/03/09)
  • HAART Does Not Reverse Premature T-Cell Aging Caused by HIV – (02/27/09)
  • Incomplete Peripheral CD4+ Cell Count Restoration in HIV-Infected Patients Receiving Long-Term Antiretroviral Treatment – (02/27/09)
  • CROI: Aging with HIV – Lessons from CROI 2009 – Victor Valcour MD – (02/27/09)
  • CROI: HIV Infection May Make the Brain 15 to 20 Years Older: HIV slows cerebral blood flow and stimulus response in MRI study – written by Mark Mascolini – (02/23/09)
  • CROI: Effects of Aging on HIV Pathogenesis: aging is associated with higher t-cell activation in women than men, effects of menopause on inflammation and immune activation….” (02/23/09)
  • CROI: Immune Senescence, Activation, and Abnormal T Cell Homeostasis despite Effective HAART, a Hallmark of Early Aging in HIV Disease: “HIV-infected subjects (median 56 years) with good immune reconstitution and viral suppression had immune changes comparable to older (median 88 years) HIV-negative subjects” – (02/20/09)
  • CROI: HIV-1 INFECTION IS ASSOCIATED WITH ACCELERATED VASCULAR AGING (02/18/09)
  • CROI: Neurocognitive (and neuropathy) Impairment Rate Remains High in Diverse US Cohort – written by Mark Mascolini – (02/18/09)
  • Causes of Accelerated Aging in HIV: HIV Induces Aging of T-Cells – (02/10/09)
  • HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity: review by Steve Deeks and Andrew Phillips – (01/28/09)
  • Aerobic + Strength Exercise is Optimal for Insulin Resistance and Improved Health & Frailty in Study of Obese and Older, Average Age 67 Yrs – (01/28/09)
  • HIV Prematurely Accelerates Aging – (01/22/09)
  • AGING AND INFECTIOUS DISEASES: effects of aging; Immunosenescence and Vaccination in Nursing Home Residents – (01/22/09)
  • Our results suggest that HIV-1 infection induces an accelerated aging of T lymphocytes, which is associated with the clinical progression to AIDS and death – (01/13/09)
  • C-Reactive Protein and Reclassification of Cardiovascular Risk in the Framingham Heart Study – (01/14/09)
  • Cardiovascular Complications in HIV Management: Past, Present, and Future [Critical Review: Clinical Science] – (01/12/09)
  • Increased Melanoma Rates in USA Are Real and Aging/HIV – (01/09/09)
  • Prospective study of physical fitness, adiposity, and inflammatory markers in healthy middle-aged men and women – (01/07/09)
  • Lipoatrophy among HIV-infected patients is associated with higher levels of depression than lipohypertrophy – (01/02/09)
  • Keeping Blood Sugar Low May Help Stem Geriatric Memory Loss – (01/02/09)
  • Central obesity and increased risk of dementia more than three decades later – (12/22/08)
  • Visceral Fat & Neurotoins, Insulin Resistance & Alzheimer Disease/Dementia EDITORIAL – (12/22/08)
  • Impaired insulin secretion increases the risk of Alzheimer disease – (12/22/08)
  • Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes – (12/22/08)
  • Associations between Male Anogenital Human Papillomavirus Infection and Circumcision by Anatomic Site Sampled and Lifetime Number of Female Sex Partners – (12/22/08)
  • Federal Government NIAID Aging Funding Opportunities – (12/16/08)
  • Neurological/Cognitive Impairment on HAART: 50% on HAART have cognitive impairment – (12/10/08)
  • 10th Intl Workshp Adverse Drug Reactions & Lipo: A Comparison of Cardiac Function Between HIV-Infected and HIV-Seronegative People With and Without the Metabolic Syndrome. – (12/10/08)
  • 10th Intl Workshp Adverse Drug Reactions & Lipo: COMPARISON OF THE EFFECTS OF NEVIRAPINE RESPECT TO EFAVIRENZ ON DIFFERENTIATING AND MATURE HUMAN ADIPOCYTES IN CULTURE – (12/10/08)
  • Poor Glycemic Control in Diabetes and the Risk of Incident Chronic Kidney Disease Even in the Absence of Albuminuria and Retinopathy – (12/09/08)
  • “elevations in inflammatory markers seen in insulin resistance, metabolic syndrome, and diabetes are not causative but a consequence of these abnormalities.” – (12/02/08)
  • Metabolic Syndrome Predicts New Onset of Chronic Kidney Disease in 5,829 Patients With Type 2 Diabetes – (12/02/08)
  • Endothelial Activation Markers Are Linked to HIV Status and Are Independent of Antiretroviral Therapy and Lipoatrophy – (12/02/08)
  • Inflammation May Be Associated with AIDS Progression – (12/02/08)
  • Uric Acid Levels Increase Risk for New-Onset Kidney Disease – Editorial – (12/02/08)
  • HIV TAT Protein Infects Brain Shortly After HIV-Infection and Disrupts Brain Normal Activity, Affects Mitochondria– Pretreatment with the RyR antagonist, dantrolene mediated these pathologic effects…..dantrolene has side effects but these findings could lead to research for therapy to block this mechanism of action “RyR may be a crucial target for neuroprotection in HIV-associated neurologic disease” – (11/19/08)
  • ICAAC: Continuous Antiretroviral Therapy Decreases Bone Mineral Density: Results from the SMART Study (11/24/08)
  • ICAAC: Bone Loss in SMART Study – Written by Mark Mascolini – (10/30/08)
  • Statin induced myopathy – (11/21/08)
  • 10th Intl Workshp Adverse Drug Reactions & Lipo: Effect of HAART on insulin sensitivity, autonomic nervous system function and beta-adrenergic mediated lipolysis (11/20/08)
  • Statin (Crestor) Prevents Heart Disease, Lowers LDL and Inflammation in Healthy with Normal Lipids – (11/18/08)
  • Statin Therapy for Prevention? EDITORIAL Expanding the Orbit of Primary Prevention – Moving beyond JUPITER – (11/18/08)
  • JUPITER hits New Orleans: Landmark study shows statins benefit healthy individuals with high CRP levels – (11/18/08)
  • Crestor Study Will Boost Statin Demand – (11/18/08)
  • The role of HIV in serious diseases (non-AIDS diseases) other than AIDS – (11/18/08)
  • Silent cardiac dysfunction and exercise intolerance in HIV+ men receiving combined antiretroviral therapies – (11/18/08)
  • Higher frequency of dementia in older HIV-1 individuals The Hawaii Aging with HIV-1 Cohort – (11/18/08)
  • Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis – (11/18/08)
  • Proinflammatory Markers, Insulin Sensitivity, and Cardiometabolic Risk Factors in Treated HIV Infection – (11/18/08)
  • 9th Interntl Drug Thrpy HIV: Cardiovascular disease; HIV, ART, immunodeficiency, pro-inflammation and other factors – (11/13/08)
  • ICAAC: Unremitting Kaposi Sarcoma in HIV infected patients with viral suppression on antiretrovirals – (10/31/08)
  • Mechanisms of Neuronal Injury and Death in HIV-1 Associated Dementia – (10/24/08)
  • The CNS HIV Antiretroviral Therapy Effects Research (CHARTER) study – (10/23/08)
  • HIV suppression by HAART preserves cognitive function in advanced, immune-reconstituted AIDS patients – (10/23/08)
  • Neurotoxic effect of HIV: HIV-1 RNA concentration and cognitive performance in a cohort of HIV-positive people – (10/23/08)
  • The prevalence and incidence of neurocognitive impairment in the HAART era (08/30/07)
  • More Alzheimer’s Risk for Hispanics, Studies Suggest – (10/21/08)
  • Diabetes in D.A.D. Study – (10/21/08)
  • Non-AIDS Deaths In HIV Positive Patients Linked To Inflammation And Coagulation Markers…and ART interruption – (10/21/08)
  • Nadir CD4 Cell Count Predicts Neurocognitive Impairment in HIV-Infected Patients – (10/21/08)
  • Association of White Blood Cell Subfraction Concentration with Fitness and Fatness – (10/17/08)
  • Aging with HIV Increases Risk for Comorbidities: Do Patterns of Comorbidity Vary by HIV Status, Age, and HIV Severity? – (10/14/08)
  • CROI: HIV and Aging at CROI 2008 – epidemiology of aging with HIV – (02/22/08)
  • Long-Term Follow-up after Tight Control of Blood Pressure in Type 2 Diabetes – (10/10/08)
  • Mitochondria and Aging – (10/09/08)
  • New Genetic Model For Parkinson’s Disease: mitochondrial damage – (10/09/08)
  • Mitochondria Damage & Aging – (10/09/08)
  • Reports of KS in Aging SF Patients – (10/06/08)
  • Can We Cure Aging? – (10/06/08)
  • Central obesity and increased risk of dementia more than three decades later – (10/03/08)
  • Impaired insulin secretion increases the risk of Alzheimer disease – (10/03/08)
  • Visceral Adiposity & Insulin Impairment & Dementia/Alzheimer’s – (10/03/08)
  • Inflammatory Markers and Incident Fracture Risk in Older Men and Women: The Health Aging and Body Composition Study – (09/2/08)
  • Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America – (05/13/05)
  • Cancers in HIV: immunity/ART – (09/26/08)
  • Estimating GFR Using Cystatin Alone & in Combination with Creatinine: analysis of 3,418 with CKD – (09/26/08)
  • Chronic Kidney Disease Prevalence Higher in the USA: related to hypertension, diabetes, aging – (09/26/08)
  • CKD in the Elderly-Old Questions and New Challenges: CKD in the elderly as a new challenge for research, clinical practice, and public health. – (09/26/08)
  • A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis – (09/26/08)
  • CROI: Incidence Anal Squamous Intraepithelial Lesions (SIL) and Predictors of in the SUN Study after One Year of Follow-up – (02/22/08)
  • CROI: Immunodeficiency and Risk of AIDS-defining and Non-AIDS-defining Cancers: ANRS CO3 Aquitaine Cohort, 1998 to 2006 – (02/25/08)
  • CROI: Insufficient Virus Suppression during HAART Is a Strong Predictor for the Development of AIDS-related Lymphoma: German CLINSURV Cohort – (02/25/08)
  • CROI: Fat Changes Boost Heart Disease and Diabetes Risk in HIV-Infected Men – Written by Mark Mascolini (02/19/08)
  • CROI: Cardiovascular Risk Markers Greatly Inflate Death Risk in People With HIV; interruptions increase risk – Written by Mark Mascolini (02/12/08)
  • CROI: Role of Antiretroviral Therapy, Viral Replication, and HIV Infection in Atherosclerosis – (03/07/08)
  • CROI: Prevalence and Risk Factors in HIV-infected Persons for Echocardiographic Abnormalities in the Era of Modern HAART – (03/05/08)
  • CROI: Inflammatory Markers Correlate with Carotid Intima-Media Thickness and Endothelial Activation in HIV-infected Patients (03/12/08)
  • Subclinical Glucose Abnormalities & Undiagnosed Diabetes Noted in HCV+ – (09/18/08)
  • Vitamin B12 & Brain Atrophy – (09/18/08)
  • Alzheimer’s Disease Risk Factors: metabolics-diabetes, cholesterol–, genetics, lifesyle – (09/18/08)
  • Mediterranean Diet Improves Health & Mortality – (09/18/08)
  • HIV, Dementia & HAART – (09/18/08)
  • Intensive Blood Glucose Control Has Positive Outcomes in ADVANCE Study – (09/12/08)
  • Aging with HIV; Early Cognitive Decline – (08/28/08)
  • Depression in the United States Household Population, 2005-2006 – (09/16/08)
  • HIV-associated Alzheimer’s disease in the Future? – (09/16/08)
  • Statins for Slowing Kidney Disease Progression: An as yet Unproven Indication – (09/16/08)
  • Frailty Defined in Older Adults Evidence for a Phenotype – (09/16/08)
  • Physical Frailty Could Predict Alzheimer’s Disease – (09/16/08)
  • Alzheimer’s Disease Risk Factors: exercise, metabolics, lifestyle, genetics – (09/16/08)
  • ACTG Bone Study Group Established; More Bone Issues Need Attention – (09/18/08)
  • Influence of HAART on the Clinical Course of HIV-1-Infected Patients With Progressive Multifocal Leukoencephalopathy: Results of an Observational Multicenter Study – (09/18/08)
  • Cidofovir in addition to antiretroviral treatment is not effective for AIDS-associated progressive multifocal leukoencephalopathy: a multicohort analysis – (09/12/08)
  • Approach to the Patient with Prediabetes – (09/08/08)
  • HCV Coinfection Increases Risk for HIV-Related Kidney Disease – (09/18/08)
  • The Inflammatory Debate: Is it the Virus, the Drugs, or the Host? – (09/18/08)
  • Highly-sensitive C-reactive protein (hsCRP) is associated with body mass index (BMI) and serum lipids in HIV-infected patients with low cardiovascular disease (CVD) risk and virologic suppression on antiretroviral therapy (ART) – (09/18/08)
  • Changes in Causes of Death Among Adults Infected by HIV Between 2000 and 2005: The Mortalite 2000 and 2005 Surveys (ANRS EN19 and Mortavic) [Epidemiology and Social Science] – (08/27/08)
  • Running slows the aging clock, Stanford researchers find – (09/02/08)
  • Earlier HAART Suggested for African-Americans At-Risk for Kidney Disease – (08/27/08)
  • HIV, HAART & Brain Damage – (09/18/08)
  • Intensive Blood Glucose Control Has Positive Outcomes in ADVANCE Study – (09/18/08)
  • Subclinical Glucose Abnormalities & Undiagnosed Diabetes Noted in HCV+ – (09/18/08)
  • HIV Infection and Dementia in Older Adults: should we be concerned? – (04/25/06)
  • HIV, HAART & Brain Damage – (11/28/05)
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